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Adult Treatment Panel III Guidelines by National Cholesterol Education Program & National Heart, Lung, and Blood Institute

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Step 8: Metabolic Syndrome

Metabolic syndrome, sometimes refered to as Syndrom X is characterized by the presence of increased fasting blood glucose, obesity (particularly in the abdominal area), elevated serum triglycerides, elevated blood pressure, and low HDL cholesterol. The combination of any 3 factors listed in the table below leads to a diagnosis.

Risk Factor Defining Level
Abdominal obesity*
Men
Women
Waist circumference**
>102 cm (>40 in)
>88 cm (>35 in)
Triglycerides >150 mg/dL
HDL cholesterol
Men
Women
<40 mg/dl
<50 mg/dl
Blood pressure 130/85 mmHg
Fasting glucose 110 mg/dL

*Excess body fat, particularly abdominal obesity, is associated with insulin resistance, the inability for the body to respond to normal insulin levels. The metabolic risk factors are more strongly correlated with abdominal obesity, measured by waist circumference, than with body mass index (BMI).

**A slight increase (37-39 in.) in waist circumference of males can result in the development
of multiple metabolic risk factors. These individuals may have a stronger genetic
contribution to insulin resistance. Changes in life style habits will benefit these males.

Treatment of Metabolic Syndrome

Metabolic syndrome can be successfully treated with Therapeutic Lifestyle Changes.
Emphasis should be placed on weight management and increased physical activity. Cholesterol, triglycerides, and other risk factors should be treated if lifestyle therapies
are ineffective after 3 months.

 
Web Tools
ATP III Guidelines
Step 1: Lipid Profile
Step 2: Presence of CHD
Step 3: Risk Factors
Step 4: 10-year Risk
Step 5: Risk Category
Step 6: TLC
Step 7: Drug Tx
Step 8: Metabolic Syndrome
Step 9: Triglycerides

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UT Southwestern Medical Center
5323 Harry Hines, Dallas, TX 75390
214-648-2890
Page created and maintained by: Lona Sandon, MEd, RD, LD
Email: NAA@UTSouthwestern.edu


Last updated: 10/3/03

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